095 Rasburicase in gout complicated by methaemoglobinaemia
نویسندگان
چکیده
منابع مشابه
Urate oxidase (rasburicase) for treatment of severe tophaceous gout.
Gout is a clinical disorder caused by deposition of urate crystals in a joint leading to acute inflammatory response with acute pain. In severe and longstanding gout, the crystals accumulate in soft tissues such as cartilage, subcutaneous tissue or even veins leading to the development of tophi responsible for very large deposit formations and disability. Most cases of gout present with the sud...
متن کاملRasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout
Hyperuricemia is a feature of several pathologies and requires an appropriate and often early treatment, owing to the severe consequences that it may cause. A rapid and massive raise of uric acid, during tumor lysis syndrome (TLS), and also a lower and chronic hyperuricemia, as in gout, mainly damage the kidney. To prevent or treat these consequences, a new therapeutic option is represented by ...
متن کاملUrate oxidase (rasburicase) for treatment of severe acute gout: a case report.
A 73-year-old female patient was referred to our department because of gouty arthritis in the right first toe. The patient suffered from progressive renal failure because of pauci-immune necrotising glomerulonephritis. As severe hyperuricaemia would further worsen progredient renal insufficiency and therapy with allopurinol was contraindicated because of renal insufficiency and previous pancyto...
متن کاملMITRAL STENOSIS COMPLICATED BY RENAL ARTERY EMBOLISM
Six patients with mitral stenosis complicated by renal artery embolism studied prospectively are presented. In five patients there was unilateral and in one patient bilateral renal artery involvement. The diagnosis was confirmed by intravenous pyelography, retrograde pyelography, renal angiography, renal scan or a combination of these. All had atrial fibrillation, proteinuria and elevated ...
متن کاملNitrite-induced methaemoglobinaemia.
Three patients developed methaemoglobinaemia after eating meat contaminated with excessive nitrites. Diagnosis was delayed in the first two mild cases but was promptly made in the third most severely affected case.
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2018
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/key075.319